Журнал структурной химии №3 2008 (341,00 руб.)

De Lang R.-J. Transition metal catalysed cross couplings in organic synthesis. <...> SDBSWeb: http: // www.aist.go.jp/RIODB/SDBS/ (National Institute of Advanced Industrial Science and Technology, 29.03.2006) Baran J., Davydova N.A., Drozd M., Pietraszko A. // J. Phys.: Condens. <...> Method for automatic removal of background // 5th Austin Symposium on Gas-Phase Molecular Structure. <...> Method for automatic removal of background // 5 Austin Symposium on Gas-Phase Molecular Structure. <...> P. 349 353. ., - . . .: - . , 1964. 2008. 49, 3 . 465 475 UDC 547.822.3; 543.429.23; 543.51 SYNTHESIS AND CONFORMATIONAL ANALYSIS OF SOME CYANOMETHYLENE DERIVATIVES OF PIPERIDINES 2008 A. Manimekalai*, J. Anusuya, J. Jayabharathi Department of Chemistry, Annamalai University, Annamalainagar 608 002, India Received 8 May, 2007 Five 4-dicyanomethylene derivatives 610, N-cyanoacetyl-cis-2,6-diphenylpiperidin-4-one 11 and 4-cyano(ethoxycarbonyl)-methylene-cis-2,6-bis(o-chlorophenyl)piperidine 12 were synthesised by condensing the appropriate piperidin-4-ones 1317 with malononitrile/ethylcyanoacetate and their 1H and 13C NMR spectra were recorded. <...> The 1H-1H COSY spectrum for 6 and NOESY spectra for 8, 10 and 11 were also recorded. <...> Based on coupling constants and the results obtained from NOESY spectra boat conformation for 10 and epimerised chair conformations for 8 and 9 have been proposed. <...> Theoretical calculations and the 1H and 13C chemical shifts also support the above conformations. <...> K e y w o r d s: molecular conformations, saturated heterocycles, six-membered heterocycles, computations, NMR spectra, mass spectra, A1,3 strain. <...> Recently Manimekalai and Anusuya [ 4 ] reported the synthesis and spectral studies of six cyanomethylene derivatives of cis-2,6-diaryltetrahydrothiopyrans 4. <...> The study of conformations of heavily substituted ring compounds possessing A1,3 strain is highly interesting since in these compounds conformational changes are expected to occur in order to avoid A1,3 strain. <...> Considerable work has been carried out on the conformational behaviour of several substituted 2,6-dialkyl- and 2,6-diarylpiperidine derivatives possessing A1,3 strain through spectral analysis [ 512 ]. <...> Therefore, there is considerable interest in the synthesis and the study of the molecular structures of cyanomethylene derivatives possessing A1,3 strain. <...> In 5 the alkyl groups at C(3 <...>