Вестник МИТХТ, 2009, т. 4, № 5
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Учредитель
МИТХТ им. М.В.Ломоносова
ХИМИЯ И ТЕХНОЛОГИЯ ЛЕКАРСТВЕННЫХ ПРЕПАРАТОВ И
БИОЛОГИЧЕСКИ АКТИВНЫХ СОЕДИНЕНИЙ
П.Е. Назаров, Г.И. Мягкова, Н.В. Гроза. Полиненасыщенные
жирные кислоты как универсальные эндогенные биорегуляторы
М.А. Ажигирова, Т.Л. Дереза, О.Г. Кутюрова, Т.А. Ципилева
Изучение сорбции комплекса факторов свертывания крови VIII и
фон Виллебранда на ионообменных сорбентах
В.П. Гудов, В.Г. Лунин, В.И. Швец. Создание модифицированных
сорбентов для твердофазного синтеза зондов для ПЦР в реальном
масштабе времени
А.Ю. Жульков, И.С. Витол, Г.П. Карпиленко. Исследование процесса
сбраживания ржаного сусла, полученного с использованием
зерновой и микробной фитаз
М.Н. Корчажникова, И.В. Назимов, Ю.М. Глубоков, В.В. Безуглов.
Хроматографический и масс-спектрометрический анализ
гликозилированного генно-инженерного инсулина человека
Е.В. Ожимкова. Кинетика ферментативного гидролиза
полисахаридов льна ксиланазой trichoderma viride
Главный редактор:
проф. Тимофеев В.С.
Зам. главного редактора:
проф. Фролкова А.К.
проф. Фомичев В.В.
ХИМИЯ И ТЕХНОЛОГИЯ ОРГАНИЧЕСКИХ ВЕЩЕСТВ
Г.А. Григорьев, E.В. Еськова, А.А. Андреянцева, В.Б. Ильиничева.
Анализ термодинамических условий образования эмульсий при
самодиспергировании
Э.П. Дяченко, И.Ю. Алексанян, Л.М. Титова. Исследование
сорбционных и термодинамических характеристик поверхностноактивного
вещества сульфонола
Иса Юсуф (Макарфи), В.Ф. Третьяков, Н.А. Французова, Л.М. Коваль,
В.И. Ерофеев, А.А. Трушин. Конверсия этанола и водноэтанольных
смесей на промышленном катализаторе HZSM-5
Н.И. Филиппова, Г.Г. Матафонова, В.Б. Батоев. Обесцвечивание
растворов азокрасителя ультрафиолетовым излучением XeBr
эксилампы
Редакционная коллегия:
доц. Биглов Р.Р.
проф. Дробот Д.В.
проф. Корнюшко В.Ф.
акад. РАН Кузнецов Н.Т.
акад. РАН Мирошников А.И.
проф. Мирошников Ю.П.
проф. Озерин А.Н.
проф. Серафимов Л.А.
проф. Сухорукова С.М.
проф. Тверской В.А.
акад. РАН Цивадзе А.Ю.
акад. РАМН Швец В.И.
доц. Юловская В.Д.
ТЕОРЕТИЧЕСКИЕ ОСНОВЫ ХИМИЧЕСКОЙ ТЕХНОЛОГИИ
Б.Б. Долматов, А.В. Тимошенко, А.Г. Волков, Е.А. Анохина.
Области энергетической оптимальности схем экстрактивной
ректификации смеси метанол – н-пропилацетат – толуол с
анилином
А.К. Фролкова, Г.И. Тациевская, Л.А. Хахин. Правило фаз и
вариантность фазовых процессов в системах с неподвижными
компонентами
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ISSN 1819-1487
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СИНТЕЗ И ПЕРЕРАБОТКА ПОЛИМЕРОВ И КОМПОЗИТОВ НА ИХ ОСНОВЕ
А.В. Артеменко, Ю.А. Наумова, Л.Р. Люсова, В.А. Глаголев.
Резинотканевые эластомерные материалы на основе
гидрированного бутадиен-нитрильного каучука
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А.И. Гуляев, Ю.Н. Филатов, Т. Х. Тенчурин. Исследование
электроформования ультратонких волокон из
полидифениленфталида
О.А. Дулина, Е.И. Свиридова, А.М. Буканов. Некоторые
особенности смачивания резин водой
П.В. Суриков, А.Н. Трофимов, Е.И. Кохан, Л.К. Щеулова,
И.Д. Симонов-Емельянов. Влияние молекулярной массы и
молекулярно-массового распределения на реологические свойства
эпоксидных олигомеров
ХИМИЯ И ТЕХНОЛОГИЯ НЕОРГАНИЧЕСКИХ МАТЕРИАЛОВ
А.С. Глухов, С.А. Григорьев. Разработка наноструктурных
катализаторов для электрохимических систем с твѐрдым
полимерным электролитом и их исследование
О.В. Петракова, Д.В. Дробот, П.А. Щеглов. Синтез и свойства
комплекса рения c n-бутанолом и i-бутанолом
© МИТХТ им. М.В. Ломоносова Abstracts
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Стр.1
Вестник МИТХТ, 2009, т. 4, № 5
Review
MITHT
5/2009
Редакция:
Агаянц И.М.
Наумова Ю.А.
Семерня Л.Г.
Середина Г.Д.
CONTENTS
CHEMISTRY AND TECHNOLOGY OF MEDICAL PRODUCTS AND
BIOLOGICALLY ACTIVE SUBSTANCES
P.E. Nazarov, G.I. Miagkova, N.V. Groza. Polyunsaturated fatty
acids as universal endogenious bioregulators
M.A. Azighirova, T.L. Dereza, O.G. Kuturova, T.A. Zipileva. Study
of adsorption of factor vVIII-VFW complex on ion-exchange
supports
V.P. Goudov, V.G. Lunin, V.I. Shvets. Preparation modified resins
for solid-phase synthesis of RT-PCR fluorescent probes
A.U. Zhulkov, I.S. Vitol, G.P. Karpilenko. Research of process of
rye wort fermentation produced with using of grain and microbial
phytase
M.N. Korchaznikova , I.V. Nazimov , Yu.M. Glubokov,
V.V. Bezuglov. Chromatographic and mass-spectrometric analysis
of glycosylated recombinant human insulin
Адрес редакции:
119571, г. Москва,
пр. Вернадского, 86,
к. Л-119
телефон: (495) 936-82-88
e-mail: vestnik@mitht.ru
Е.V. Оzhimkova. Kinetics of flax polysaccharides enzymatic
hydrolysis by Trichoderma viride xylanase
CHEMISTRY AND TECHNOLOGY OF ORGANIC SUBSTANCES
G.A. Grigoriev, E.V. Eskova, A.A. Andreyantseva, V.B. Ilinicheva.
Thermodynamic conditions of emulsion formation during
autodispersion
E.P. Dyachenko, I.Y. Aleksanyan, L.M. Titova. Research sorption and
thermodynamic characteristics of surface-active substance of sulfonol
Подписано в печать
19.10.2009 г. Формат 60x90/8.
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Гарнитура Times.
Печать офсетная.
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Заказ № 342.
Тираж 500 экз.
Isa Yusuf (Y.I. Makarfi), V.F.Tretyakov, N.A. Frantsuzova,
L.M. Koval, V.I. Erofeev, A.A. Trushin. Conversion of ethanolwater
mixture over industrial HZSM-5 catalyst
N.I. Philippova, G.G. Matafonova, V.B. Batoev. Decolorization of azo dye
in aquoeos solutions by ultraviolet irradiation of XeBr excilamp
THEORETICAL BASED OF CHEMICAL TECHNOLOGY
B.B Dolmatov, A.V. Timoshenko, A.G. Volkov, E.A. Anokhina.
Different flowsheets isoenergetic manifolds being generated in
methanol – propylacetate – toluene extractive distillation with
aniline
A.K. Frolkova, G.I. Tatsievskaya, L.A. Khakhin. Rule of phases and
variance of phase processes in systems with fixed components
Отпечатано с оригинал-макета в
«ГЕЛИОПРИНТ»
119602, Москва, Ак. Анохина, 38, к. 1
SYNTHESIS AND PROCESSING OF POLYMERIC COMPOSITES
А.V. Artemenko, Y.A. Naumova, L.R. Lusova, V.A. Glagolev.
Rubberized fabrics based on hydrogenated nitryl-butadiene rubber
A.I. Gulajev, Yu.N. Filatov, T.H. Tenchurin. Investigation of
polydiphenylenephthalide nanofibers electrospining
O.A. Dulina, E.I. Sviridov, A.M. Bukanov. Some especially moisten
rubbers of water
P.V. Surikov, A.I. Trofimov, E.I. Kohan, L.K. Sheulova,
I.D. Simonov-Emelianov. Influence of MM and MMD on
rheological properties of epoxy resins
CHEMISTRY AND TECHNOLOGY OF INORGANIC MATERIALS
A.S. Glukhov, S.A. Grigoriev. Development and research of nanostructured
catalysts for electrochemical systems with solid polymer
electrolyte
O.V.Petrakova, D.V. Drobot, P.A. Scheglov. Synthesis and
properties rhenium complex with n-butanol and i-butanol
Abstracts
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«Вестник МИТХТ», 2009, т. 4, № 5
ABSTRACTS
P.E. Nazarov, G.I. Miagkova, N.V. Groza. Polyunsaturated fatty acids as universal endogenious
bioregulators.
Studying of a physiological role of natural polyunsaturated fatty acids (PUFAs) at a new step of
development of scientific and technical progress is actual. The present review is devoted
questions of biosynthesis PUFAs, their regulatory functions, distribution in tissues lipids of an
animal organism. In the review new effective methods of isolation and identification of unsaturated
fatty acids and their metabolites from biological objects, such as extraction under pressure, a
capillary nuclear magnetic resonance, a combination of a liquid chromatography and mass
spectrometry also are considered.
M.A. Azighirova, T.L. Dereza, O.G. Kuturova, T.A. Zipileva.Study of adsorption of factor vVIIIVFW
complex on ion-exchange supports.
We investigated the binding capacity for FVIII/vWF complex of five different anion-exchange
supports, DEAE-Toyopearl 650M, Toyopearl Super Q-650M, Fractogel EMD TMAE (M), DEAE
Sepharose FF, Fractogel EMD TMAE Hicap (M). The chromatographic supports with tentacle
structure demonstrated the best results. The adsorption was performed by a batch-method when
mixing at the room t0 and a residual FVIII and vWF-content was measured in the supernatant. The
maximum binding capacity was estimated 188 IU FVIII /g and 2309 IU vWF /g for Fractogel EMD
TMAE (M) and 134 IU FVIII /g and 1935 IU vWF /g for Fractogel EMD TMAE Hicap (M). The
results obtained may be used for development of the method of purifying a FVIII/vWF complex
using ion-exchange chromatography.
V.P. Goudov, V.G. Lunin, V.I. Shvets. Preparation modified resins for solid-phase synthesis of RTPCR
fluorescent probes.
Synthesis of library functional anchor groups with xanthene fluorescent dye on solid-phase
support. Prepared CPG can be used for synthesis fluorescent probes for RT-PCR
A.U. Zhulkov, I.S. Vitol, G.P. Karpilenko. Research of process of rye wort fermentation produced
with using of grain and microbial phytase.
This paper is devoted to influence of various factors (option of wort production, strain of yeast,
duration of fermentation) for the process of fermentation rye wort. The effect of endogenous and
microbial phytase on the accumulation of ethanol and volatile impurities is investigated.
M.N. Korchaznikova , I.V. Nazimov , Yu.M. Glubokov ,V.V. Bezuglov. Chromatographic and massspectrometric
analysis of glycosylated recombinant human insulin.
The recombinant modified peptides and proteins method of structure and properties determination
has been considered by the example of the glycosylated gene-spliced human insulin with
disaccharide.
Е.V. Оzhimkova. Kinetics of flax polysaccharides enzymatic hydrolysis by Trichoderma viride
xylanase.
The present work is devoted to kinetics of flax polysaccharides enzymatic hydrolysis by Trichoderma
viride xylanase study.
G.A. Grigoriev, E.V. Eskova, A.A. Andreyantseva, V.B. Ilinicheva. Thermodynamic conditions of
emulsion formation during autodispersion.
The thermodynamic conditions of emulsion formation are considered on the basis of perfect
solution model. It is shown that the factor chosen arbitrarily in the article of Shchukin-Rebinder on
the determination of critical surface tension, can be calculated on the basis of experimentally
definable quantities. It is established that the thermodynamic conditions of the formation of
emulsion from a two-phase initial state depend on the initial interphase tension and the structure
of initial system. It is noted that the contribution of mixture enthropy to the general
thermodynamical properties of the system becomes apparent at a high degree of the
dispersiveness close to molecular one. To achieve the conditions of dispersion the introduction of
the mechanical energy or the energy of the combined process proceeding at the interphase border
in parallel with the dispersion process is necessary.
E.P. Dyachenko, I.Y. Aleksanyan, L.M. Titova. Research sorption and thermodynamic characteristics of
surface-active substance of sulfonol.
The statics of process of dehydration and property of synthetic surface-active substance of
sulfonol as object of drying is investigated. Are experimentally received and isotherms of sorbtion
of sulfonol are mathematical described. As a result of the analysis of curves of sorbtion
conclusions are drawn on change of the form of communication of a moisture with a material,
recommendations for choice final humidity of a dried up product are made. The analysis of
thermodynamics internal mass exchange is carried out at interaction of sulfonol with water.
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«Вестник МИТХТ», 2009, т. 4, № 5
Isa Yusuf (Y.I. Makarfi), V.F.Tretyakov, N.A. Frantsuzova, L.M. Koval, V.I. Erofeev,
A.A. Trushin. Conversion of ethanol-water mixture over industrial HZSM-5 catalyst.
This work is devoted to investigating the effects of ethanol space velocity and the composition of
ethanol-water mixture on their conversion to hydrocarbons over the industrial
3%Zn/27%Al2O3/Fe-ZKE-G50 (Si/Fe = 550) catalyst. It was shown that at 350ºC, the relationship
between ethanol space velocity and liquid hydrocarbons yield passes through a maximum at
around 2h-1. Increasing ethanol space velocity to 5-10h-1 leads to increase in ethylene formation
and a loss in selectivity for other hydrocarbons. Increasing the amount of water, drastically
reduces the yield of liquid hydrocarbons. A high selectivity for C3-C4 hydrocarbons can be obtained
using a mixture with ethanol to water ratio of 2:1. Further increase in water content leads to a
decrease in the ethylene oligomerisation rate, consequently resulting in an increase in ethylene
formation. Water addition to ethanol plays an important role in the overall process selectivity
without altering the catalyst and technological equipment.
N.I. Philippova, G.G. Matafonova, V.B. Batoev. Decolorization of azo dye in aquoeos solutions by
ultraviolet irradiation of XeBr excilamp.
The efficiency of decolorization of azo dye Direct Blue KM in aqueous solutions by ultraviolet
irradiation of XeBr excilamp (282 nm) in the range of initial concentrations of hydrogen peroxide
and pH values was studied. The optimum operation conditions were determined.
B.B Dolmatov, A.V. Timoshenko, A.G. Volkov, E.A. Anokhina. Different flowsheets isoenergetic
manifolds being generated in methanol – propylacetate – toluene extractive distillation with aniline.
This work is devoted for investigation of isocriterial manifolds and isocriterial fields arrangement
into initial feed composition simplex. That fields and manifolds dividing of them are formed at
methanol - n-propylacetat – toluene with aniline extractive distillation. Initial mixture contains one
binary azeotrop with minimum boiling point (in methanol – toluene pair) and one tangential
azeotrop in methanol - n-propylacetat pair near the pure n-propylacetat. In the capacity of the
optimization criteria was chosen heating capacities on the distillation columns reboilers.
A.K. Frolkova, G.I. Tatsievskaya, L.A. Khakhin. Rule of phases and variance of phase processes in
systems with fixed components.
The rule of phases for systems with fixed components and variance of phase processes in such
systems, including variance of one-stage phase processes and process of extractive rectification
taking into account intensive, extensive and constructive variables is considered.
А.V. Artemenko, Y.A. Naumova, L.R. Lusova, V.A. Glagolev. Rubberized fabrics based on
hydrogenated nitryl-butadiene rubber
Aspects of creation rubberized fabrics which keep working capacity in a wide interval of temperatures and
are characterized by high durability to various aggressive environments are considered.
A.I. Gulajev, Yu.N. Filatov, T.H. Tenchurin. Investigation of polydiphenylenephthalide nanofibers
electrospining
Polymer-solvent system for producing electrospun polydiphenylenephthalide nanofibrous
materials is developed. Uniform fibers with diameters up to 0.3 mkm are received. Thermostable
filter materials can be produced using developed system.
O.A. Dulina, E.I. Sviridov, A.M. Bukanov. Some especially moisten rubbers of water
Moisten rubbers of water defined by edge corner moisten right away after surface clearing by
solvent, is depended from polymer nature. The least polymer polarity, the least is less moisten. By
determine of moisten it is necessary to consider that surface is changed quickly after clearing by
volatile solvents as result of emanate of rubber low-molecular components.
P.V. Surikov, A.I. Trofimov, E.I. Kohan, L.K. Sheulova, I.D. Simonov-Emelianov. Influence of
MM and MMD on rheological properties of epoxy resins
The molecular characteristics of diane epoxy oligomers produced by industries: DER-330, ED-20, ED-16,
ED-8 is studied. The fractional composition was identified. The viscosity characteristics epoxy resins at
different temperature are studied the entire range of molecular weight and molecular-mass distribution.
A.S. Glukhov, S.A. Grigoriev. Development and research of nano-structured catalysts for
electrochemical systems with solid polymer electrolyte.
Technique of synthesis of high-effective nanostructured electrocatalysts on carbon carrier for
electrochemical systems with proton-exchange membrane (PEM) is described, their structural and
electrochemical properties are investigated. Current-voltage curves of membrane-electrode
assemblies (MEA) on the basis of synthesized electrocatalysts within PEM fuel cell, water
electrolyser and reversible cell are obtained.
O.V.Petrakova, D. V. Drobot, P. A.Scheglov. Synthesis and properties rhenium complex with nbutanol
and i-butanol.
First rhenium oxobutoxoderivatives with n-BuOH and i-BuOH have been obtained by
electrochemical method. The decomposition rhenium complex with n-BuOH at 412°С in oxidizing
atmosphere results in obtaining oxides of Re(VI) and Re(IV) in the condensed phase.
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«Вестник МИТХТ», 2009, т. 4, № 5
Вестник МИТХТ
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