To study the dynamics of the basic indicators of iron metabolism of red blood cells of peripheral blood from regular donors of blood depending on the amount of donations and the duration time of the donor’s experience Materials and methods. <...> The donor experience was more than 10 years. <...> The average number of donations from male donors was 46.42±1.23 donation, with individual variations from 37 to 59, women - donors – 46.23±4.45 at the individual fl uctuations from 38 to 64. <...> Were determined in serum iron content and measure serum total iron binding capacity for bаtofenantrolin method. <...> Indicator unsaturated iron binding capacity of serum was calculated as the diff erence between total iron binding capacity and serum iron content. <...> Ratio of transferrin saturation with iron was defi ned as the ratio of iron content to the iron binding capacity of serum. transferrin content was determined in terms of the total iron binding capacity of serum ferritin – radiometric method. <...> Signifi cant disturbance of iron metabolism in the red blood cells of peripheral blood of active donors, which manifest the formation of latent iron defi ciency. <...> The use of tablets iron supplementation for the prevention and correction of disorders of iron metabolism in blood donors active successfully eliminates not only iron defi ciency but also related metabolic disorders. <...> It is proved that the development of iron defi ciency in blood donors is not always accompanied by changes in peripheral blood and rate of hemoglobin, which is used in Blood Service to evaluate iron metabolism in the body of blood donors. <...> Шупика, Референс-центр по молекулярной диагностике Министерства здравоохранения Украины, Киев, Украина , Rossokha Z.2 , Gorovenko N.1 , Gartovska I.1 , Salah A.A. Abushanab1 1 Shupyk National Medical Academy of Post-Graduate education, Kyiv, Ukraine 2 Reference-center for molecular diagnostic of Public Health Ministry of Ukraine, Kyiv, Ukraine Особенности течения лимфом с учетом полиморфизма генов Тр53, Lmyc, CYP2D6, CYP2С19 Features of lymphomas course based on Тр53, Lmyc, CYP2D6, CYP2С19 gene polymorphism Цель исследования. <...> В работе показаны результаты оценки диагностического <...>