Сумский государственный университет, Сумы, Украина Aluminum, cadmium and lead content in serum and erythrocytes in newborns with disturbance kidney function due to asphyxia Содержание алюминия, кадмия и свинца в сыворотке крови и эритроцитах новорожденных детей с нарушением функции почек вследствие асфиксии ______________________ Abstract __________________________________________________________________________ The aim of the investigation is explore the features of the content and balance of toxic electrolytes (aluminum, cadmium and lead) in serum and red blood cells of newborns with disturbance of kidneys function due to asphyxia. <...> Investigation included 200 full-term newborns with the signs of renal damage: 100 neonates suff ered from severe asphyxia, and 100 babies suff ered from moderate asphyxia. <...> A comparison group comprised 20 infants without asphyxia at birth. <...> Blood was collected on the 1–2 day of life, in the end of the early neonatal period (7–8 day of life), and at the end of the fi rst month (25–30 day). <...> For newborns with impaired renal function had typical high level of Al, Cd, Pb in blood serum during early neonatal period in case of moderate asphyxia or predominantly during whole 1st month of life in case of severe form. <...> Prolonged increase levels of toxic elements in erythrocytes were more specifi c for neonates with kidneys function disturbance due to severe asphyxia. <...> Transmembrane ratio of all investigated toxic elements indicated on the preferred movement of ions inward the cell. <...> Renal dysfunction can be formed on the fi rst day of life on the background of tissue hypoxia due to metabolic disorders, hemodynamic disturbance and violation of microcirculation [1]. <...> Non-essential metals such as aluminum (Al), cadmium (Cd) and lead (Pb) are ubiquitous persistent environmental toxicants known to bioaccumulate in the human body. <...> The placenta can take up some of the toxic ions very actively and then transmitted them to fetus [5]. <...> The aim of the investigation is explore the features of the content and balance of toxic electrolytes (aluminum, cadmium and lead) in serum and red blood cells of newborns with disturbance kidney function due to asphyxia. <...> MATERIALS AND METHODS Investigation included 200 full-term newborns with the signs of renal damage. <...> A comparison group comprised 20 infants <...>