Demidenkoa,b and Tatiana G. Volovaa,b aSiberian Federal University, , 79 Svobodny, Krasnoyarsk, 660041, Russia b 50/50 Akademgorodok, Krasnoyarsk, 660036, Russia Received 07.08.2014, received in revised form 18.08.2014, accepted 21.08.2014 On the basis of experimentally achieved and developed technical and technological parameters of biosynthesis processes the baseline data were obtained and the project was worked out for organization of pilot production of degradable polyhydroxyalkanoates (PHAs). <...> The pilot line for production of polyhydroxyalkanoates was designed, equipped and commissioned, including the “Bioengineering” fermentation line (Switzerland), as well as the blocks for preparation of inoculum and culture media, isolation and purifi cation of polymers. <...> When the initial concentration of inoculum was (10 ± 2) g/l and the cultivation duration was 65 h, the fi nal concentrations of cells biomass in the culture of Cupriavidus eutrophus В10646 and polymer were (110±10) g/l and (85±5)%, with the process productivity by biomass and PHA of 1.7 and 1.4 g/l·h, respectively, which is twice as high as the previously achieved results in the culture of Ralstonia eutrophus B5786 on fructose. <...> Scaling the technology made it possible to obtain the experimental batches of polymers in the amounts needed for conducting a complex of prescribed research, development and standardization of specialized polymer products. <...> All rights reserved * Corresponding author E-mail address: evgeniygek@gmail.com Institute of Biophysics SB RAS, # 134 # Evgeniy G. <...> Масштабирование технологии синтеза биодеградируемых полигидроксиалканоатов в условиях опытного производства Е.Г. Киселева,б С.В. Барановскийа,б , А.В. Демиденкоа,б , Т.Г. Воловаа,б Россия, 660041, Красноярск <...>