UDC 621 NON-NEWTONIAN ANALYSIS OF DRUG ELUTING STENTS © Sayan Bose Future Institute of Engineering and Management, Kolkata, INDIA Amitava Datta Jadavpur University, Kolkata,INDIA Ranjan Ganguly Jadavpur University, Kolkata,INDIA Moloy Banerjee Future Institute of Engineering and Management, Kolkata, INDIA Abstract. <...> Numerical investigation of drug-eluting stents has been performed, to assess the drug deposition along the arterial wall under non-Newtonian flow. <...> An Eulerian-Lagrangian approach is used to resolve the hemodynamic flow, using ANSYS FLUENT, and the drug concentration is obtained by solving the mass transport equation simultaneously. <...> It has been found that changing the flow from Newtonian to non-Newtonian results in increase of drug deposition along the arterial wall and variation of other physical parameters reveals the performance of drug-eluting stents under non-Newtonian flow. <...> Though endovascular stents reduces chances of re-stenosis but more recent, use of drug eluting stents (DES) has proven effective in treating re-stenosis [1, 5]. <...> Performance parameters of the stents are dependent on its geometry, as well as other physical parameters under both steady and unsteady f low, and flow parameters are also influenced by the stent geometries producing small recirculation zones next to the stent walls [2]. <...> The purpose of this investigation is to reveal the variation of performance parameters under non-Newtonian f low, so that better understanding can be obtained, that how these stents behave under proper physiological conditions as human blood is non-Newtonian. <...> Numerical model The model consists of a 2-dimensional view of an artery with reduced stents. <...> The cross-section of the stents is taken to be square of side (d) equal to 0.4 mm. The stent to artery ratio (d/D) is taken to be 0.1 where D is the artery diameter. <...> The upstream and downstream length of the domain is taken to be 2D each, and the inter stent distance is taken as d [3]. <...> Parametr ic s tudy i s per formed for di f ferent Reynolds number and depth ratio (DR), where DR is def ined as the fraction of stent side exposed to the blood. <...> Blood is considered non-Newtonian and steady state simulation <...>