УДК 54.057/8:542 Yan-Hua Cai*, D.A. Filimonov**, Yan-Hua Zhang* SYNTHESIS OF N,N'-BIS(BENZOYL) DODECANEDIOIC ACID DIHYDRAZIDE AND EFFECT ON NUCLEATION AND MECHANICAL PROPERTIES OF POLY(L-LACTIC ACID) (*School of Materials and Chemical Engineering, ChongQing University of Arts and Sciences, YongChuan,ChongQing, P.R. China, **Ivanovo State University of Chemistry and Technology, Ivanovo, Russia) e-mail: caiyh651@yahoo.com.cn, daf81@mail.ru routes, and the structure of NA had been confirmed by FT-IR, 1H NMR. <...> Compared to the neat PLLA, with the addition of 0.8% NA, the crystallization temperature (To) increase from 105.88 °C to 125.07 °C and the crystallization enthalpy (ΔHc) increase from 1.379 J•g-1 to 29.17 J•g-1 at a cooling rate of 1 °C/min from melt. <...> And the impact strength possesses a maximum value for the critical NA loading 1%. <...> N,N'-Bis(benzoyl) dodecanedioic acid dihydrazide (NA) was synthesized by a advanced Key words: Benzoyl hydrazine, Dodecanedioic Acid, Poly(L-lactic acid), Nucleation INTRODUCTION Poly(L-lactic acid)(PLLA) is a semicrystalline polymer with numerous desirable properties: lower energy consumption, biopolymer and non-toxic to the environment [1], Thus, it is widely used in biomedical applications [2], packaging materials [3-5] to automotive interior [6]. <...> However, PLLA still has some disadvantages, such as slow crystallization rate, low crystalline degree and poor heat resistance. <...> For all applications, it is of major importance to improve the crystallization characteristics of PLLA, which strongly affect its application. <...> In recent years, amide and its derivatives as important organic compounds had been widely used in synthesis of intermediates [7] and materials chemistry [8], drugs release [9], polymers [10,11], etc, and obtained a lot of progress. <...> And some synthesized compounds were found to be evidently effective in vitro against lung cell line. <...> The distinctly marked antiproliferative effect of some compounds in breast carcinoma cells in vitro was ascertained. <...> There existed some literature [10] which reported amide could improved the crystallization of PLLA, Thus, in this paper, we synthesis N, N'Bis(benzoyl) dode-canedioic acid dihydrazide as a nucleating agent to improve the crystallization of PLLA <...>