Фабрика антител (717,11 руб.)

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内容简介 《抗体工厂》共分五十八章，就抗体的基本特性以及制备流程进行全面论述，同时 对抗体测序、抗体药物开发也进行了必要的阐述。本书紧密结合应用实际，着重介绍抗 体的最新理论和最新技术，具有很强的科学性、实用性和先进性，同时配以大量的技术 路线示意图，是一本不可多得的抗体技术参考书籍，适于医学相关专业人员阅读参考。 图书在版编目（ C I P ）数据 责任编辑：孟祥刚 天津出版传媒集团 天津科学技术出版社 出版 出版人：蔡 颢 天津市西康路 35 号 邮编 300051 电话（022）23332695 网址：www.tjkjcbs.com.cn 新华书店经销 天津午阳印刷有限公司印刷 开本 787×1092 1/16 印张 8 字数 100 000 2018 年 6 月 第 1 版第 1 次印刷 定价：88.00 元

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《抗体工厂》编委会名单 （按姓名汉语拼音排序） 康星 李翀 陶涛 王建华 杨昭 张旭 张怡 朱学加

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目 录 第一章 什么是抗体 ··············································································································· 1 第二章 抗体的基本结构 ······································································································· 5 第三章 抗体的生物学功能 ·································································································· 10 第四章 抗原的分类详解 ····································································································· 13 第五章 抗原决定簇与抗原特异性 ······················································································ 16 第六章 抗原抗体的相互作用 ······························································································ 20 第七章 免疫佐剂的分类、作用及机制 ·············································································· 23 第八章 如何选择一抗和二抗 ······························································································ 25 第九章 如何正确保存抗体 ·································································································· 28 第十章 多克隆抗体与单克隆抗体的区别 ··········································································· 31 第十一章 单克隆抗体的基本概念、原理及制备流程和应用 ············································ 34 第十二章 杂交瘤技术简述及基本原理 ·············································································· 38 第十三章 杂交瘤细胞系如何建立 ······················································································ 42 第十四章 杂交瘤筛选——选择培养基筛选 ······································································· 45 第十五章 杂交瘤筛选——特异性抗体筛选 ······································································· 47 第十六章 杂交瘤细胞克隆方法 ·························································································· 51 第十七章 高通量测序技术对抗体研发的影响 ··································································· 53 第十八章 抗体人源化简介及其应用 ·················································································· 57 第十九章 人-鼠嵌合抗体简介及基本原理 ········································································· 60 第二十章 AbSeq抗体测序 ··································································································· 63 第二十一章 免疫球蛋白A（IgA）抗体测序 ······································································ 67 第二十二章 免疫球蛋白E（IgE）抗体测序 ······································································· 69 第二十三章 免疫球蛋白M（IgM）抗体测序 ····································································· 71 第二十四章 免疫球蛋白G（IgG）抗体测序 ······································································ 73 第二十五章 新型纳米抗体测序 ·························································································· 75 第二十六章 偶联抗体测序 ·································································································· 76 第二十七章 人抗体或人源化抗体测序 ··············································································· 77 第二十八章 仿制药抗体测序 ······························································································ 79 第二十九章 鼠抗体测序 ····································································································· 80 ·1·

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抗体工厂 第三十章 羊抗体测序 ····································································································· 82 第三十一章 兔抗体测序 ····································································································· 83 第三十二章 鸡抗体IgY测序 ······························································································· 84 第三十三章 杂交瘤细胞抗体基因测序 ··············································································· 86 第三十四章 多物种单克隆抗体制备 ·················································································· 88 第三十五章 驼源单克隆抗体制备 ······················································································ 89 第三十六章 猴（NHP）单克隆抗体制备 ··········································································· 91 第三十七章 人源单克隆抗体制备 ······················································································ 92 第三十八章 豚鼠单克隆抗体制备 ······················································································ 94 第三十九章 仓鼠单克隆抗体制备 ······················································································ 96 第四十章 鸡IgY单克隆抗体的制备 ················································································ 98 第四十一章 大鼠单克隆抗体制备 ····················································································· 100 第四十二章 小鼠单克隆抗体制备 ····················································································· 102 第四十三章 鲨单克隆抗体制备 ························································································· 104 第四十四章 狗源单克隆抗体制备 ····················································································· 105 第四十五章 兔单克隆抗体制备 ························································································· 106 第四十六章 多物种多克隆抗体制备 ················································································· 108 第四十七章 鸡IgY多克隆抗体制备 ··················································································· 109 第四十八章 兔多克隆抗体制备 ························································································· 111 第四十九章 驼科多克隆抗体制备 ····················································································· 113 第五十章 羊多克隆抗体制备 ························································································· 115 第五十一章 膜蛋白抗体制备 ····························································································· 116 第五十二章 DNA免疫制备抗体 ························································································ 118 第五十三章 抗体药物开发 ································································································· 120 第五十四章 全人单克隆抗体开发 ····················································································· 122 第五十五章 稳定细胞系构建 ····························································································· 123 第五十六章 人源化单克隆抗体开发 ················································································· 125 第五十七章 亲和力成熟 ···································································································· 127 第五十八章 ADCC活性检测 ······························································································ 129 ·2·

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