В исследование включен 61 ребенок с ЛМ в возрасте 0–5 лет. <...> ЛМ определяли соответственно новой ISSVA классификации (Мельбурн, 2014) как кистозные, первичная лимфедема и смешанные. <...> В соответствии с методом лечения пациенты разделены на 4 группы: консервативное лечение (n=8), ОК-432 склеротерапия (n=34), хирургическое (n=9) и комбинированное лечение (OK-432 + хирургическое (n=5), хирургическое + консервативное (n=2), OK-432 + консервативное лечение (n=3)). <...> ОК-432 склеротерапия выполнена у 34 детей с кистозными ЛМ. <...> Внедрение склеротерапии обеспечивает минимально инвазивный способ лечение ЛМ и уменьшает процент осложнений. <...> Unfortunately there is no cure for some type of LM. <...> Young children is the most difficult group to solve the time and method of treatment. <...> In this study 61 child aged 0–5 years with LM are enrolled. <...> The diagnosis of LM is confirmed by MRI. <...> LMs were classified according the new ISSVA classification (Melbourne, 2014) as common (cystic), primary lymphedema, and combined. 10 patients were diagnosed with primary lymphedema, 48 –with cystic LM, primary lymphedema with cystic LM took place in 3 children. <...> The most common localization of cystic LM is the head and neck region (85.4%), bilateral lesions were in 21.9% children, 12.2% had mediastinal portion. <...> Patients were divided into four groups according to the method of treatment: conservative treatment (n=8), OK-432 sclerotherapy (n=34), surgical (n=9) and combined treatment (OK-432 + surgery (n=5), surgery +conservative therapy (n=2), OK-432 + conservative therapy (n=3)). <...> Results: Patients with primary lymphedema (n=8) were managed conservatively by combination of decongestive lymphatic therapy with compression therapy. <...> OK-432 sclerotherapy was performed in 34 children with cystic LM. <...> Among complications the only case of skin allergic reaction (n=1) was registered. <...> Response to treatment was most successful in neck unilateral, isolated macrocystic LM (95.2%). <...> Indications for operative treatment were the recurrent inflammation, massive bleeding in the cyst, allergic reaction to penicillin, and microcystic form. <...> Postoperative complications were the following: LM recurrence in 3 <...>