The authors analyzed the influence of a genotype, climatic conditions and agronomic methods of plant growing on -glucans content in barley corn. <...> Thus, it was fixed the negative correlation between -glucans content in barley grain on the one hand and value of 1000seeds mass, amylose and starch content, ash percent, corn yield — on the other hand. <...> The strong positive correlation was found between the content in corn of glucans, lipids, protein and the grain-unit and its hardness. <...> It was shown, that glumaceous amylose-free varieties are more advanced agronomically (in arid climate, especially), as they are able to realize a substantial potential of yield with high content of -glucans. <...> Barley is one of major cereal crops in the world; its gross grain yield is estimated as the fifth after wheat, maize, rice, and sorghum. <...> Healthy functional nutrition has been in focus of increasing interest in recent years, especially soluble dietary fiber from cereals as dietary supplements. <...> Cell walls of the endosperm of barley, oats, and other cereal crops were found to contain specific polysaccharides so-called (1,3;1,4)-β-D-glucans having the property to decrease blood cholesterol and sugar levels, reduce the risk of cardiovascular disease and diabetes, and efficient prevention and treatment of some serious human diseases including colon cancer; these substances may help to reduce body weight due to a lasting sense of satiety, they strengthen the immune system and show antimicrobial activity (2-5). <...> The mechanisms by which soluble dietary fibers such as -glucans promote the reduce in blood cholesterol and glucose levels are yet insufficiently clear and widely discussed in the literature. <...> Furthermore, the said polysaccharides inhibit the absorption of nutrients, primarily carbohydrates, reduce hyperglycemia and insulin secretion. <...> Along with it, healthy nutrition considers the value of products prepared from other cereal crops, particularly rye and oats. <...> In rodent experiments, -glucans derived from both barley and oat grain provided almost equal activity of reducing blood cholesterol level (19). <...> However, it should be noted that some studies didn’t reveal any significant physiological effects of diets supplemented with barley -glucans. <...> Along with the abovementioned positive effects of polysaccharides from cell walls of the cereal <...>